Peer-reviewed Publications: PAAR-Dolan 2005-2009

  1. Liu W., Innocenti F., Wu M.H., Desai A., Dolan M.E., Cook E.H., Ratain, M.J. A functional common polymorphism in an Sp1 recognition site of the epidermal growth factor receptor gene promoter. Cancer Res., 65:46-53, 2005. PMID 15665278
  2. Zhang, W., Bleibel, W.K., Roe, C.R., Cox, N.J., Dolan, M.E. Gender-specific Differences in Expression in Lymphoblastoid Cell Lines. Pharmacogenetics and Genomics, 17: 447-450, 2007. PMID 17502836
  3. Huang, R.S., Kistner, E.O., Bleibel, W.K., Shukla, S.J., Dolan, M.E. Effect of Population and Gender on Chemotherapeutic Agent-induced Cytotoxicity. Molecular Cancer Therapeutics, 6(1); 31-36, 2007. PMID 17237264
  4. Huang, R. S., Duan, S., Bleibel, W. K. Kistner, E. O., Zhang, W., Clark, T. A., Chen, T.X., Schweitzer, A.C., Blume, J. E., Cox, N. J. and Dolan, M. E. A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity, PNAS, 104: 9758-9763, 2007. PMID 17537913
  5. Hartford, C.; Yang, W.; Cheng, C.; Fan, Y.; Trevino, L.; Pounds, S.; Neale, G.; Raimond, S.C.; Bogni, A.; Dolan, M.E.; Pui, C-H.; Relling, M.V. Genome scan implicates adhesion biological pathways in secondary leukemia. Leukemia, 21(10):2128-36. 2007.
  6. Huang, R.S., Duan, S., Shukla, S.J., Kistner, E.O., Clark, T.A., Chen, T.X., Schweitzer, A.C., Blume, J.E., Dolan, M.E. Identification of genetic variants contributing to Cisplatin-induced cytotoxicity using a genome-wide approach. Amer. J. Human Gen., 81(3):427-37. 2007 PMID 17701890
  7. Duan, S., Bleibel, W.K., Huang, S.R., Shukla, S.J., Wu, X., Badner, J.A., Dolan, M.E. Mapping genes that contribute to Daunorubicin-induced cytotoxicity. Cancer Res., 67(11):5425-5433, 2007. PMID 17545624
  8. Zhang, W., Duan, S., Kistner, E. O., Bleibel, W. K., Huang, R. S., Clark, T. A., Chen, T. X., Schweitzer, A.C., Blume, J. E., Cox, N. J. and Dolan, M. E. Evaluation of Genetic Variation Contributing to Differences in Gene Expression Between Populations. Amer. J. Human Genetics, 82: 631-640, 2008. PMID 18313023
  9. Shukla, S.J., Duan, S., Badner, J.A., Wu, X., and Dolan, M.E. Susceptibility Loci Involved in Cisplatin-Induced Cytotoxicity and Apoptosis. Pharmacogenetics and Genomics, 18: 253-262, 2008. PMID 18300947
  10. Huang, R. S., Duan, S., Kistner, E. O., Bleibel, W. K. Delaney, S.M. Fackenthal, D. L., Das, S. and Dolan, M. E. Genetic Variants Contributing to Daunorubicin-Induced Cytotoxicity. Cancer Research, 68:3161-3168, 2008. PMID 18451141
  11. Duan, S., Huang, R.S., Zhang, W., Bleibel, W.K., Roe, C.A., Clark, T.A., Chen, T.X., Schweitzer, A.C., Blume, J.E., Cox, N.J., and Dolan, M.E. Genetic Architecture of Transcript-Level Variation in Humans. Amer. J. Human Genetics, 82:1101-1113, 2008. PMID 18439551
  12. Huang, R.S., Duan, S., Kistner, E.O., Zhang, W., Bleibel, W.K., Cox, N. J. and Dolan, M.E. Identification of Genetic Variants and Gene Expression Relationships Associated with Pharmacogenes in Human. Pharmacogenetics and Genomics, 18:545-549, 2008. PMID 18496134
  13. Huang, R.S., Duan. S, Kistner, E.O., Hartford, C.M., Dolan, M.E. Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans. Molec Cancer Ther., 7(9): 3038-3046, 2008. PMID 18765826
  14. Yang, J., Bogni, A., Cheng, C., Bleibel, W.K., Cai, X., Fan, Y., Yang, W., Rocha, J.C.C., Pei, D., Liu, W., Dolan, M.E, Pui, C.H., and Relling, M.V. Etoposide Sensitivity Does Not Predict MLL Rearrangements or Risk of Therapy-related Acute Myeloid Leukemia. Clinical Pharmac Ther., 84: 691-697, 2008. PMID 18509329
  15. Hartford, C.M., Duan, S., Delaney, S.M., Mi, S., Kistner, E.O., Lamba, J.K., Huang, R.S., and Dolan, M.E. Population Specific Genetic Variants Important in Susceptibility to Cytarabine Arabinoside Cytotoxicity. Blood, 113(10):2145-53, 2009. PMID 19109566
  16. Duan, S., Cox, N., Dolan, M.E. FstSNP-HapMap3: a database of SNPs with High Population Differentiation for HapMap3. Bioinformation, in press, 2009. PMID 19238253
  17. Bleibel, W.K., Duan, S., Huang, R.S. Kistner, E.O., Shukla, S.J., Wu, K., Badner, J.A., and Dolan, M.E. Identification of genomic regions contributing to etoposide-induced cytotoxicity. Human Genetics, 125(2):173-80, 2009. PMID 19089452
  18. Zhang, W., Duan, S., Bleibel, W.K., Wisel, S.A., Huang, R.S., Wu, X., He, L., Clark, T.A., Chen, T.X., Schweitzer, A.C., Blume, J.E., Dolan, M.E., Cox, N.J. Identification of Common Genetic Variants that Account for transcript isoform variation between Populations. Hum Genet., 125, 81-93, 2009. PMID 19052777
  19. Shukla, S.J., Duan, S., Wu, X., Badner, J.A., Kasza, K., and Dolan, M.E. Whole Genome Approach Implicates CD44 in Cellular Resistance to Carboplatin. Human Genomics, 3, 128-142, 2009. PMID 19164090
  20. Duan S, Zhang W, Bleibel WK, Cox NJ, Dolan ME. SNPinProbe_1.0: A database for filtering out probes in the Affymetrix GeneChip(R) Human Exon 1.0 ST array potentially affected by SNPs. Bioinformation 2(10):469-70, 2008. PMID 18841244
  21. Huang, R.S., Chen, P., Wisel, S., Duan, S., Zhang, W., Cook, E.H., Das, S., Cox, N.J., and Dolan, M.E. Population Specific GSTM1 Copy Number Variation. Human Mol Genet, 18: 366-372, 2009. PMID 18948376
  22. Zhang, W, Huang, S and Dolan, M.E. Gene Set Enrichment Analyses Revealed Differences in Gene Expression Patterns between Males and Females. In Silico Biology, 9:6, 2009.
  23. Gamazon, E.R., Zhang, W, Huang, R.S., Dolan, M.E., Cox, N.J. A pharmacogene database enhanced by the 1000 Genomes Project. Pharmacogenet Genomics. 2009. PMID 19745786
  24. Gamazon, E.R., Zhang W., Konkashbaev A., Duan S., Kistner E., Nicolae D.L., Dolan, M.E., Cox, N.J. SCAN: SNP and CNV Annotation. Bioinformatics Advance Access published on November 17, 2009. doi:10.1093/bioinformatics/btp644


  1. Shukla, S.J. and Dolan, M.E. Use of CEPH and nonCEPH cells in pharmacogenetic studies. Pharmacogenomics, 6:303-310, 2005.
  2. Giacomini, K.M., Brett, C.M., Altman, R.B., Benowitz, N.L., Dolan, M.E., Flockhart, D.A., Johnson, J.A., Krauss, R.M., Kroetz, D.L., McLeod, H.L., Ratian, M.J., Relling, M.V., Roden, D.M., Schaefer, C.A., Shuldiner, A.R., Skaar, T., Tyndale, R.F., Weinshilboum, R.W., Weiss, S.T., Zineh, I. The pharmacogenetics research network: From SNP discovery to clinical drug response. Clin Pharm Ther., 81(3); 328-45, 2007.
  3. Hartford, C.M. and Dolan, M.E. Identifying Genetic Variants that Contribute to Chemotherapy-Induced Cytotoxicity. Pharmacogenetics, 8(9):1159-1168, 2007. PMID 17924831
  4. Zhang, W., Ratain, M.J., and Dolan, M.E. The HapMap Resource is Providing New Insights into Ourselves and its Application to Pharmacogenomics. Bioinformatics and Biology Insights, 2:15-23, 2008. PMID 18392109
  5. Zhang, W. and Dolan, M.E. Ancestry-related Differences in Gene Expression: Findings may Enhance Understanding in Health Disparities between Populations. Pharmacogenomics, 9:489-492, 2008. PMID 18466094
  6. Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM. Creating and evaluating genetic tests predictive of drug response. Nat Rev Drug Discov. 7:568-74, 2008. PMID 18587383
  7. Zhang, W. and Dolan, M.E. Beyond the HapMap Genotypic Data: Prospects of Deep Resequencing Projects. Current Bioinformatics, 3:178-182, 2008.
  8. Zhang, W. and Dolan, M.E. On the Challenges of the HapMap Resource. Bioinformation, 2:238-239, 2008. PMID 18317571
  9. Zhang, W., Duan, S., and Dolan, M.E. HapMap filter 1.0: A tool to preprocess the HapMap genotypic data for association studies. Bioinformation, 2:322-324, 2008. PMID 18685717
  10. Zhang, W. and Dolan, M.E. Exploring the evolutionary history of the differentially expressed genes between human populations: action of recent positive selection. Evolutionary Bioinformatics Online, 4:171-179, 2008. PMID 19030115 PMCID PMC2585739
  11. Zhang, W., Huang, R.S., and Dolan, M.E. Integrating epigenomics into pharmacogenomic studies. Pharmacogenomics and Personalized Medicine, 1: 7.14, 2008.
  12. Zhang, W., Huang, R.S., and Dolan, M.E. Cell-based models for discovery of pharmacogenomic markers of anticancer agent toxicity. Trends in Cancer Research, 2009